Manny Pacquiao knocked down Miguel Cotto twice and turned his face into a bloody mess before finally stopping him 55 seconds into the 12th round on Saturday to win his seventh title in seven weight classes.

The Filipino star used his blazing speed and power from both hands to cement his stature as the best pound-for-pound boxer in the world.

Cotto took such a beating that his face was a river of red from the fury of Pacquiao's punches but he refused to quit even as his corner tried to throw in the towel after the 11th round.

The fight was billed as a 145-pound classic, and in the early rounds it didn't disappoint. The two went after each other with a vengeance and Cotto more than held his own as they traded punches in the center of the ring.

Pacquiao dropped Cotto with a right hand early in the third round, but he wasn't badly hurt and came back to finish the round strong. But after Pacquiao put Cotto on the canvas with a big left hand as Cotto was advancing forward late in the fourth round, the Puerto Rican was never the same again. "Our plan was not to hurry but to take our time," Pacquiao said. "It was a hard fight tonight and I needed time to test his power."

Cotto fought gamely but in the later rounds he was just trying to survive as blood flowed down his face and Pacquiao kept coming after him relentlessly. In the 12th, Cotto went back out to take even more punishment before a final flurry along the ropes prompted referee Kenny Bayless to stop the fight.

Cotto's wife and child, who were at ringside, left after the ninth round, unable to watch the beating any longer. They later accompanied him to a local hospital for a post-fight examination.

"I didn't know from where the punches were coming," Cotto said. "Manny Pacquiao is one of the best boxers I ever fought."

Pacquiao, coming off spectacular wins over Oscar De La Hoya and Ricky Hatton, added another one against Cotto, who had lost only once and held the WBO version of the welterweight title.

The fight will likely set up an even bigger fight against Floyd Mayweather Jr, and many in the capacity crowd at the MGM Grand arena in Las Vegas began chanting, "We want Floyd! We want Floyd" after the fight ended.

Mayweather may have second thoughts after Pacquiao did what no fighter has done before and win a belt in a seventh weight class. More impressive, though, is how he has fought, dismantling opponents despite moving up consistently in weight.

The welterweight ranks will be the last ones Pacquiao conquers, though. He said he will not move up any more in weight. "This is the last weight division for me. It's history for me and more importantly a Filipino did it."