Yum Brands Inc investors on Wednesday filed a shareholder proposal requesting that it quickly phase out harmful antibiotic use in its meat supply, taking aim at the practices of the company's KFC fried chicken chain.

The proposal from shareholder activists As You Sow, of Oakland, California, and the Sisters of St Francis of Philadelphia comes as KFC lags rivals McDonald's Corp, Chick-fil-A, Subway and Wendy's Co in setting policies to curb the routine use of antibiotics in chicken production.

Those policies are a first step for many fast-food chains that are under pressure to help combat the rise of dangerous "superbugs," as antibiotic-resistant bacteria are known.

Yum's Taco Bell chain has committed to stop using antibiotics important to human medicine in its chicken supply early next year and the company's Pizza Hut chain has made a similar promise for the chicken used in its pizza toppings. KFC, which buys far more chicken than its two sister brands, has not made a similar promise.

Some 70 percent of antibiotics vital for fighting infections in humans are sold for use in meat and dairy production.

Veterinary use of antibiotics is legal. However, as the number of human infections from antibiotic-resistant bacteria rises, consumer advocates and public health experts have campaigned to end the routine use of antibiotics important to human medicine for growth promotion or illness prevention in farm animals that are not sick.

Advocates have targeted KFC because it has far more restaurants than any other fast-food chicken chain and is second in sales behind Chick-fil-A, which has committed to finishing its switch to chicken raised without any antibiotics by the end of 2019.

McDonald’s USA last week said it completed its move to chicken raised without antibiotics vital to human medicine. Wendy's plans to make a similar switch by 2017.

KFC has said that by 2017, antibiotics important for human medicine will only be used to maintain chicken health and only under the supervision and prescription of a licensed veterinarian. As per federal government guidance, KFC does not allow the use of such antibiotics for growth promotion.

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