Zvjezdan Misimovic scored twice for second-placed Wolfsburg in the last seven minutes -- his second goal deep into injury time -- to stun Braga 3-2.
CSKA went ahead through 18-year-old striker Alan Dzagoev in the 31st minute with his third Group H goal, and Yuri Zhirkov doubled the lead with a volley in first-half stoppage time.
Semir Stilic threatened a Lech comeback when he pulled one back for the Polish visitors in the 66th with a 25-meter (yard) free kick.
While CSKA has won all three matches, once-mighty Feyenoord lies bottom of the group with no points.
Spurs manager Harry Redknapp is confident they will progress after a second straight win in the competition at Nijmegen.
"With six points it's job done," Redknapp said. "It was difficult, the pitch wasn't particularly good and it was difficult to pass the ball, but we were strong and solid and never felt in any danger."
Jamie O'Hara headed into an unguarded goal in the 14th after striker Fraizer Campbell, on loan from Manchester United, rattled the crossbar.
Ivan Saenko gave Spartak Moscow a crucial win at Dinamo Zagreb ahead of its final Group D match at Spurs.
Manchester City showed that the newly wealthy Premier League side doesn't need Robinho to win matches, comfortably defeating Schalke with the Brazil forward out with an ankle injury.
Robinho's place was taken by Daniel Sturridge, who provided the cross that Benjani Mwaruwari slotted into an open goal at the far post in the 32nd minute.
Having had a goal ruled out for offside, Stephen Ireland slotted the ball under the advancing Schalke goalkeeper Manuel Neuer in the 66th.
City's next opponent, Paris St. Germain, was held 2-2 by Racing Santander after squandering a two-goal lead and stay bottom of Group A.
In Group F, Leonardo pushed four-time European champion AJAX Amsterdam up to second with a 1-0 win at Hamburg, and MSK Zilina and Slavia Prague won their first points by drawing 0-0.
Luciano Galletti scored in the first minute and set up two goals as Olympiakos routed Benfica 5-1 in Group B, where leader Galatasaray lost 1-0 at home to Metalist Kharkiv.
In Group G, 2004 champion Valencia routed Rosenborg 4-0 to claim its first win, while French league strugglers St. Etienne progressed despite Brugge's Ronald Vargas canceling out David Gigliotti's opener.
(Agencies via Shanghai Daily November 28, 2008)