At least four people were killed on Saturday morning when U.S. drones attacked a house in Pakistan' s northwestern tribal region of South Waziristan, local media reported.

According to the reports, the drones targeted a house in the Ghowa Khowa area of South Waziristan, one of Pakistan's restive tribal regions bordering Afghanistan.

The drones fired four missiles at the house in Ghowa Khowa area, some four kilometers away from the Wana district of the region.

According to eyewitnesses, two drones took part in the attack that totally destroyed the house.

Local people reached the site to start the rescue operation and took out the dead bodies from the debris.

Local media while quoting some sources reported that in the attack two militant commanders were killed but there were no official words on it.

It was the 18th drone strike of its kind (counted on daily basis) in Pakistan's northwestern regions since the start of this year in which at least 125 people have been reportedly killed.

Pakistan, on a number of occasions, showed reservation and protested over such attacks by the U.S. drones.

Different Pakistani circles have termed these attacks a serious violation of its sovereignty and a breach of the international law but the United States always defended its stance and considered it an effective way to eliminate militants hiding in Pakistan's northwestern hilly areas.

According to some reports, hundreds of innocent people have also been killed in such attacks as the collateral damage.

The Pakistani parliament unanimously passed a resolution against the drone strikes but that has failed to stop such attacks.

The U.S. and other forces fighting in Afghanistan believe that Pakistan's northwestern tribal regions are the safe heavens for the militants who allegedly attack NATO forces in Afghanistan.

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